Decitabine


CAS No:
2353-33-5
Synonyms:
5-Aza-2'-deoxycytidine
4-Amino-1-(2-deoxy-b-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one
5-Aza-2'-deoxy-D-cytidine
2′-Deoxy-5-azacytidine
Product Code:
NA02969
MDL No:
MFCD00043011
Chemical Formula:
C8H12N4O4
Molecular Weight:
228.21
Product Structure
References:
1. Bender CM et al (1998). Inhibition of DNA methylation by 5-aza-2'-deoxycytidine suppresses the growth of human tumor cell lines. Cancer Res. 58(1):95-101.
2. Momparler RL (2005). Pharmacology of 5-Aza-2'-deoxycytidine (decitabine). Semin Hematol. 42(3 Suppl 2): S9-16.
3. Shin DY et al (2012). Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation. Int J Oncol. 41(3):910-8.

 

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