R-(-)-3-Quinuclidinol


CAS No:
25333-42-0
Synonyms:
(R)-(-)-3-Hydroxyquinuclidine
(R)-(-)-1-Azabicyclo[2.2.2]octan-3-ol
Solifenacin EP Impurity E
Product Code:
FQ02772
MDL No:
MFCD13191732
Chemical Formula:
C7H13NO
Molecular Weight:
127.18
Product Structure
References:
1. Basavaiah, D et al (1996). The Baylis-Hillman reaction: A novel carbon-carbon bond forming reaction. Tetrahedron 52(24): 8001-8062.,
Shang, Y et al (2009). Novel Sc(OTf)3/3-HQD Catalyst for Morita–Baylis–Hillman Reaction. Synth Commun 39(6): 10335-1045.
2. Drewes, SE and Roos GHP (1988). Synthetic potential of the tertiary-amine-catalysed reaction of activated vinyl carbanions with aldehydes. Tetrahedron 44(15):4653-4670., Sterling, GH et al (1993). 3-Carbamyl-N-allylquinuclidinium bromide. Effects on cholinergic activity and protection against soman. Biochem Pharmacol 45(2):465-72.
3. Häring D anad Schreier P (1999). Cross-linked enzyme crystals. Curr Opin Chem Biol 3(1):35-38., Ticehurst, MD et al (2000). Characterisation of the influence of micronisation on the crystallinity and physical stability of revatropate hydrobromide. Int J Pharm 193(2):247-59.
4. Leusch, A et al (2000). Pharmacokinetics of the M1-agonist talsaclidine in mouse, rat, rabbit and monkey, and extrapolation to man. Xenobiotica 30(8): 797-8013., Wallan, A et al (1997). In vivo consequences of M1-receptor activation by talsaclidine. Life Sci 60(13-14): 977-984.
5. Reiner, E et al (1999). 3-Hydroxyquinuclidinium derivatives: synthesis of compounds and inhibition of acetylcholinesterase. Chem Biol Interact 119-120:173-81.

 

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